Anti-inflammatory results of moxifloxacin on IL8IL-1beta and TNF-alpha secretion and NF kappaB and MAP-kinase activation in human monocytes stimulated with Aspergillus fumigatus
OBJECTIVE
We now have beforehand proven that moxifloxacin conferred protecting anti-inflammatory results in opposition to Candida pneumonia in immunosuppressed mice. Additional in vitro research confirmed anti-inflammatory results of moxifloxacin in LPS and cytokine-stimulated monocytic and epithelial cells. Within the current examine, concentrating on a more difficult pathogen of immunosuppressed hosts, we studied the impact of moxifloxacin on cytokine secretion and sign transduction mechanisms in monocytic cells stimulated with Aspergillus fumigatus.
METHODS
Human peripheral blood monocytes (PBMCs) and a human monocytic cell line (THP-1) had been incubated with 1.5×10(6)/mL conidia of a scientific isolate of A. fumigatus. Cytokine secretion and activation of NFkappaB and the MAP-kinases ERK1/2 and p38 had been measured with and with out the addition of moxifloxacin (5-20 mg/L).
Human Interleukin-8 (IL-8) Antibody
RESULTS
Stimulation of PBMCs and THP-1 cells with A. fumigatus elevated IL-8, IL-1beta and TNF-alpha secretion (4.1-, 8.3- and 7-fold, and 5.4-, 3.7- and 17.8-fold, respectively). Addition of moxifloxacin (5-20 mg/L) inhibited cytokine secretion as much as 45.7+/-5%, 72+/-13% and 73+/-10% in PBMCs and as much as 35.6+/-0.5%, 30+/-2.4% and 19+/-4% in THP-1 cells (P<0.05). Sign transduction research confirmed that incubation of THP-1 cells with A. fumigatus elevated ERK1/2 and p38 phosphorylation and p65-NFkappaB protein expression by 1.6-, 1.3- and 1.8-fold, respectively. Addition of moxifloxacin inhibited ERK1/2, p38 and p65-NFkappaB by as much as 69+/-14%, 58+/-3% and 75+/-15%, respectively.
Anti-CXCL8 / IL-8 Reference Antibody (Genentech anti-IL-8) |
E24CHA784 |
EnoGene |
100 μg |
EUR 225 |
Description: Available in various conjugation types. |
Human IL-8 |
90258-A |
BPS Bioscience |
5 µg |
EUR 130 |
Description: Recombinant human Interleukin-8 is a disulfide-linked monomer protein consisting of 78 amino acid residues, migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Interleukin-8 mature chain was expressed in E. coli. |
Human IL-8 |
90258-B |
BPS Bioscience |
25 µg |
EUR 205 |
Description: Recombinant human Interleukin-8 is a disulfide-linked monomer protein consisting of 78 amino acid residues, migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Interleukin-8 mature chain was expressed in E. coli. |
Anti-IL-8 Antibody |
A2062-100 |
Biovision |
100 µg |
EUR 472.8 |
Anti-IL-8 Antibody |
A00423 |
BosterBio |
1 mL |
EUR 1444.8 |
Description: Rabbit Polyclonal IL-8 Antibody. Validated in IP, WB and tested in Human. |
Anti-IL-8 antibody |
STJ97710 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Mouse monoclonal to IL-8. |
Anti-IL-8 antibody |
STJ97717 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Mouse monoclonal to IL-8. |
Anti-IL-8 antibody |
STJ97720 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Mouse monoclonal to IL-8. |
Anti-IL-8 antibody |
STJ98175 |
St John's Laboratory |
100 µl |
EUR 280.8 |
Description: Mouse monoclonal to IL-8. |
Anti-IL-8 Antibody |
R1511-15 |
HUABIO |
100ul |
EUR 189 |
|
Anti-IL-8 Antibody |
ER1706-67 |
HUABIO |
100ul |
EUR 189 |
|
Description: Interleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. IL-8, also known as neutrophil chemotactic factor, has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also stimulates phagocytosis once they have arrived. IL-8 is also known to be a potent promoter of angiogenesis. In target cells, IL-8 induces a series of physiological responses required for migration and phagocytosis, such as increases in intracellular Ca2+, exocytosis (e.g. histamine release), and the respiratory burst. IL-8 can be secreted by any cells with toll-like receptors that are involved in the innate immune response and has been demonstrated to be a signatory chemokine of CR2+ naive T cells, also known as recent thymic emigrants. Usually, it is the macrophages that see an antigen first, and thus are the first cells to release IL-8 to recruit other cells. Both monomer and homodimer forms of IL-8 have been reported to be potent inducers of the chemokine receptors CXCR1 and CXCR2. The homodimer is more potent, but methylation of Leu25 can block the activity of homodimers. |
Anti-IL-8 Antibody |
ER1901-61 |
HUABIO |
100ul |
EUR 189 |
|
Description: IL-8, also known as neutrophil chemotactic factor, has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also stimulates phagocytosis once they have arrived. IL-8 is also known to be a potent promoter of angiogenesis. In target cells, IL-8 induces a series of physiological responses required for migration and phagocytosis, such as increases in intracellular Ca2+, exocytosis (e.g. histamine release), and the respiratory burst.IL-8 can be secreted by any cells with toll-like receptors that are involved in the innate immune response. Usually, it is the macrophages that see an antigen first, and thus are the first cells to release IL-8 to recruit other cells. Both monomer and homodimer forms of IL-8 have been reported to be potent inducers of the chemokine receptors CXCR1 and CXCR2. The homodimer is more potent, but methylation of Leu25 can block the activity of homodimers. |
Anti-IL-8 Antibody |
Y123169 |
ABM |
100 µl |
EUR 320 |
anti-IL-8 (3E4D8) |
LF-MA30011 |
Abfrontier |
100 ul |
EUR 448.8 |
Description: Mouse Monoclonal to IL-8 |
human-anti-human-IL-8-mAb(1H) |
E409C16-hA100 |
EnoGene |
Inflammation-Storm-Antibodies |
EUR 276.5 |
Description: Inflammation Storm Antibodies |
human-anti-human-IL-8-mAb(2H) |
E409C16-hB100 |
EnoGene |
Inflammation-Storm-Antibodies |
EUR 276.5 |
Description: Inflammation Storm Antibodies |
mAb mouse anti-human IL-8 |
CT264 |
U-CyTech |
0.5 mg |
EUR 312 |
mouse anti-human IL-8 mAb |
E409C16-m100 |
EnoGene |
100μL |
EUR 395 |
Description: Available in various conjugation types. |
Rabbit anti-IL-8 Antibody |
YLD4345-100ul |
Shanghai YL Biotech |
100 ul |
EUR 320 |
|
Description: Rabbit polyclonal antibody to IL-8 |
Rabbit anti-IL-8 Antibody |
YLD4345-50ul |
Shanghai YL Biotech |
50 ul |
EUR 200 |
|
Description: Rabbit polyclonal antibody to IL-8 |
Rabbit anti-IL-8 Antibody |
DL90596A-100ul |
DL Develop |
100 ul |
EUR 270 |
|
Description: CXCL8; Interleukin-8; IL-8; C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor |
Rabbit anti-IL-8 Antibody |
DL90596A-50ul |
DL Develop |
50 ul |
EUR 189 |
|
Description: CXCL8; Interleukin-8; IL-8; C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor |
Human IL-8 Protein |
abx060803-25ug |
Abbexa |
25 ug |
EUR 644.4 |
|
Human IL-8 Protein |
abx060804-25ug |
Abbexa |
25 ug |
EUR 644.4 |
|
Human IL-8 protein |
PRP1022-100ug |
Abbkine |
100 μg |
EUR 449 |
Description: Human IL-8 protein, expressed in E. coli |
Human IL-8 protein |
PRP1022-10ug |
Abbkine |
10 μg |
EUR 59 |
Description: Human IL-8 protein, expressed in E. coli |
Human IL-8 protein |
PRP1022-1mg |
Abbkine |
1 mg |
EUR 2609 |
Description: Human IL-8 protein, expressed in E. coli |
Human IL-8 protein |
PRP1022-50ug |
Abbkine |
50 μg |
EUR 249 |
Description: Human IL-8 protein, expressed in E. coli |
Anti-IL-8 Monoclonal Antibody |
A00423-1 |
BosterBio |
100ul |
EUR 476.4 |
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat. |
Recombinant Human IL-8 |
P0180 |
FN Test |
100ug |
EUR 626.83 |
|
Description: Recombinant Human protein for IL-8 |
Recombinant Human IL-8 |
SJB05-01 |
Amyotop |
25µg/vial |
EUR 342 |
Human Interleukin-8 (IL-8) Antibody (Biotin Conjugate) |
13102-05021 |
AssayPro |
150 ug |
EUR 313.2 |
Anti-Human IL-8 (I8-S2) Antibody |
Y052802 |
ABM |
100 µg |
EUR 490 |
Human IL-8 ELISA antibody pair |
CT748-10 |
U-CyTech |
10-plate |
EUR 656.4 |
Human IL-8 ELISA antibody pair |
CT748-20 |
U-CyTech |
20-plate |
EUR 1118.4 |
human DIAplex Human Inflammation - IL-8, IL-17a, |
M880130004 |
Tecan Benelux |
1 unit |
EUR 681.23 |
Rabbit anti-Human IL-8 mAb (CAP) |
RM17646 |
Abclonal |
100μg |
Ask for price |
Rabbit anti-Human IL-8 mAb (DET) |
RM17647 |
Abclonal |
100μg |
Ask for price |
Rabbit anti-Human IL-8 mAb (CAP) |
RM17648 |
Abclonal |
100μg |
Ask for price |
Rabbit anti-Human IL-8 mAb (DET) |
RM17649 |
Abclonal |
100μg |
Ask for price |
Human IL-8 Antibody (Biotin Conjugate) |
33486-05121 |
AssayPro |
150 ug |
EUR 442.8 |
Human Interleukin 8 (IL-8) CLIA Kit |
abx195916-96tests |
Abbexa |
96 tests |
EUR 990 |
|
Human Interleukin 8,IL-8 ELISA KIT |
201-12-0090 |
SunredBio |
96 tests |
EUR 528 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human Interleukin 8, IL-8 ELISA KIT |
CSB-E04641h-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid (CSF), tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human Interleukin 8, IL-8 ELISA KIT |
1-CSB-E04641h |
Cusabio |
-
EUR 600.00
-
EUR 4082.40
-
EUR 2184.00
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid(CSF), tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human Interleukin 8(IL-8)ELISA Kit |
GA-E0129HM-48T |
GenAsia Biotech |
48T |
EUR 346.8 |
Human Interleukin 8(IL-8)ELISA Kit |
GA-E0129HM-96T |
GenAsia Biotech |
96T |
EUR 559.2 |
Human IL-8(Interleukin 8) ELISA Kit |
EH0205 |
FN Test |
96T |
EUR 571.5 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human Interleukin 8,IL-8 ELISA Kit |
SL1004Hu |
Sunlong |
96 Tests |
EUR 468 |
|
Human Interleukin 8(IL-8)ELISA Kit |
NSL1931Hu |
Sunlong |
96 wells |
EUR 468 |
|
Human Interleukin 8 (IL-8) ELISA Kit |
AE38177HU-48Tests |
Abebio |
48 Tests |
EUR 200 |
|
Description: Human (Homo sapiens) |
Human Interleukin 8 (IL-8) ELISA Kit |
AE38177HU-96Tests |
Abebio |
96 Tests |
EUR 360 |
|
Description: Human (Homo sapiens) |
Human Interleukin 8(IL-8)ELISA Kit
CONCLUSIONS
Our outcomes point out that moxifloxacin acts as an anti-inflammatory agent in monocytic cells stimulated with A. fumigatus conidia. Whether or not these results could also be protecting as within the Candida pneumonia mannequin is unknown and deserves in vivo research in fashions of pulmonary aspergillosis.
Human pores and skin mast cells quickly launch preformed and newly generated TNF-alpha and IL-Eight following stimulation with anti-IgE and different secretagogues
- A number of teams have beforehand reported that rodent or human leukemic mast cells produce inflammatory cytokines akin to TNF-alpha and IL-Eight in addition to the pro-allergic cytokines IL-4, IL-5 and IL-13. Comparatively little is understood, nonetheless, relating to the flexibility of regular human pores and skin mast cells to secrete these components following both IgE-dependent or IgE-independent modes of activation.
CXCL8 Antibody, Biotin conjugated | CXCL8 Antibody, FITC conjugated
- We subsequently investigated whether or not regular human pores and skin mast cells produce these cytokines following stimulation by quite a lot of secretagogues. Enriched remoted pores and skin mast cells launched each TNF-alpha and IL-Eight following activation with both anti-IgE, SCF, substance P, compound 48/80 or A23187. This launch was dose- and time-dependent, with maximal ranges being reached inside Four h of stimulation involving, partly, the secretion of preformed shops of each cytokines.
Anti-IL8/CXCL8 Antibody |
PB9621 |
BosterBio |
100ug/vial |
EUR 400.8 |
Anti-IL8/CXCL8 Antibody |
PA1353 |
BosterBio |
100ug/vial |
EUR 400.8 |
Human CXCL8 ELISA Kit |
STJ150098 |
St John's Laboratory |
1 kit |
EUR 494.4 |
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IL-8 in human serum, plasma and other biological fluids |
Human Interleukin-8 (CXCL8) |
1-CSB-YP011671HU |
Cusabio |
-
EUR 516.00
-
EUR 280.80
-
EUR 1809.60
-
EUR 770.40
-
EUR 1210.80
-
EUR 349.20
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Interleukin-8(CXCL8),partial expressed in Yeast |
Human Interleukin-8 (CXCL8) |
1-CSB-EP011671HU |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Interleukin-8(CXCL8),partial expressed in E.coli |
CXCL8 antibody |
70R-21501 |
Fitzgerald |
50 ul |
EUR 522 |
Description: Rabbit polyclonal CXCL8 antibody |
CXCL8 Antibody |
1-CSB-PA009564 |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/40000 |
CXCL8 Antibody |
1-CSB-PA15789A0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Gallus gallus. This antibody is Unconjugated. Tested in the following application: ELISA |
CXCL8 Antibody |
1-CSB-PA004977 |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000 |
CXCL8 Antibody |
1-CSB-PA08327A0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
CXCL8 Antibody |
1-CSB-PA08329A0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200 |
CXCL8 Antibody |
1-CSB-PA011671GA01HU |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC |
CXCL8 Antibody |
1-CSB-PA011671YA01DO |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from dog. This antibody is Unconjugated. Tested in the following application: ELISA |
CXCL8 Antibody |
1-CSB-PA003036 |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000 |
CXCL8 Antibody |
E912452 |
EnoGene |
100ul |
EUR 255 |
Description: Available in various conjugation types. |
CXCL8 Antibody |
E91289 |
EnoGene |
100ul |
EUR 255 |
Description: Available in various conjugation types. |
Human CXCL8 Protein, Fc Tag |
E40KMPH1200 |
EnoGene |
20ug |
EUR 495 |
Human CXCL8 Protein, Fc Tag |
E40KMPH1201 |
EnoGene |
20ug |
EUR 495 |
Human CXCL8 Protein, Fc Tag |
E40KMPH1203 |
EnoGene |
20ug |
EUR 495 |
Human CXCL8 Protein, Fc Tag |
E40KMPH1204 |
EnoGene |
20ug |
EUR 495 |
Human CXCL8 Protein, Fc Tag |
E40KMPH1205 |
EnoGene |
20ug |
EUR 495 |
Human CXCL8 Protein, Fc Tag |
E40KMPH5724 |
EnoGene |
20ug |
EUR 495 |
Human CXCL8 Protein, His Tag |
E40KMPH1202 |
EnoGene |
20ug |
EUR 495 |
Human CXCL8 Protein Lysate 20ug |
IHUCXCL8PLLY20UG |
Innovative research |
each |
EUR 213 |
|
Description: Human CXCL8 Protein Lysate 20ug |
Anti-bovine IL-8 (CXCL8) antibody |
STJ15100008 |
St John's Laboratory |
250 µg |
EUR 403.2 |
Description: These monoclonal antibodies enable sensitive and specific detection of bovine IL-8 in ELISpot. |
Anti-bovine IL-8 (CXCL8) antibody |
STJ15100009 |
St John's Laboratory |
250 µg |
EUR 403.2 |
Description: This monoclonal antibody enables sensitive and specific detection of bovine IL-8 in ELISA. |
CXCL8 ELISA Kit (Human) (OKAN04343) |
OKAN04343 |
Aviva Systems Biology |
96 Wells |
EUR 950.4 |
Description: Description of target: The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is secreted primarily by neutrophils, where it serves as a chemotactic factor by guiding the neutrophils to the site of infection. This chemokine is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other members of the CXC chemokine gene family form a gene cluster in a region of chromosome 4q.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 2 pg/mL |
CXCL8 ELISA Kit (Human) (OKAN04344) |
OKAN04344 |
Aviva Systems Biology |
96 Wells |
EUR 950.4 |
Description: Description of target: The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is secreted primarily by neutrophils, where it serves as a chemotactic factor by guiding the neutrophils to the site of infection. This chemokine is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other members of the CXC chemokine gene family form a gene cluster in a region of chromosome 4q.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.7 pg/mL |
CXCL8 ELISA Kit (Human) (OKAN04345) |
OKAN04345 |
Aviva Systems Biology |
96 Wells |
EUR 950.4 |
Description: Description of target: The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is secreted primarily by neutrophils, where it serves as a chemotactic factor by guiding the neutrophils to the site of infection. This chemokine is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other members of the CXC chemokine gene family form a gene cluster in a region of chromosome 4q.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.7 pg/mL |
Human CXCL8 Recombinant Protein Lyophilized |
IHUCXCL8RLY5UG |
Innovative research |
each |
EUR 341 |
|
Description: Human CXCL8 Recombinant Protein Lyophilized |
Human IL-8/CXCL8 ELISA Kit |
RK00011 |
Abclonal |
96 Tests |
EUR 625.2 |
Human CXCL8/ Interleukin-8 ELISA Kit |
E0623Hu |
Sunlong |
1 Kit |
EUR 582 |
IL-8/CXCL8 (CHO-expressed), Human |
HY-P7379 |
MedChemExpress |
50ug |
EUR 596.4 |
CXCL8 Polyclonal Antibody |
A55395 |
EpiGentek |
-
EUR 684.66
-
EUR 117.70
-
EUR 302.50
-
EUR 423.50
|
- 100 µg
- 20 ul
- 50 ul
- 100 ul
|
CXCL8 Polyclonal Antibody |
A51853 |
EpiGentek |
-
EUR 684.66
-
Ask for price
-
Ask for price
-
EUR 423.50
|
- 100 µg
- 20 ul
- 50 ul
- 100 ul
|
CXCL8 Polyclonal Antibody |
A52034 |
EpiGentek |
-
EUR 684.66
-
EUR 117.70
-
EUR 302.50
-
EUR 423.50
|
- 100 µg
- 20 ul
- 50 ul
- 100 ul
|
CXCL8 Polyclonal Antibody |
E92541 |
EnoGene |
100ul |
EUR 255 |
Description: Available in various conjugation types. |
Human Interleukin 8 / IL8 (CXCL8) Protein |
20-abx260688 |
Abbexa |
-
EUR 4101.60
-
EUR 393.60
-
EUR 276.00
|
|
|
Human IL-8 / CXCL8 Protein, Fc Tag |
IL8-H5258 |
ACROBIOSYSTEMS |
100ug |
EUR 2749.9 |
|
Description: Human IL-8, Fc Tag (IL8-H5258) is expressed from human 293 cells (HEK293). It contains AA Ser 28 - Ser 99 (Accession # P10145-1). |
Human IL-8 / CXCL8 Protein, His Tag |
IL8-H52H3 |
ACROBIOSYSTEMS |
100ug |
EUR 2749.9 |
|
Description: Human IL-8, His Tag (IL8-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 28 - Ser 99 (Accession # P10145-1). |
Recombinant Human Interleukin-8 (CXCL8) ,partial |
RPC25857-100ug |
Biomatik Corporation |
100ug |
EUR 460.9 |
Human Interleukin 8 / IL8 (CXCL8) ELISA Kit |
20-abx152049 |
Abbexa |
-
EUR 6373.20
-
EUR 3404.40
-
EUR 801.60
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Interleukin 8 / IL8 (CXCL8) ELISA Kit |
abx251378-96tests |
Abbexa |
96 tests |
EUR 764.4 |
|
Human Interleukin 8 / IL8 (CXCL8) ELISA Kit |
abx050129-96tests |
Abbexa |
96 tests |
EUR 745.2 |
|
Human Interleukin 8 / IL8 (CXCL8) ELISA Kit |
abx574561-96tests |
Abbexa |
96 tests |
EUR 764.4 |
|
Human Interleukin 8 / IL8 (CXCL8) ELISA Kit |
20-abx156661 |
Abbexa |
-
EUR 6768.00
-
EUR 3610.80
-
EUR 848.40
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
CXCL8/IL-8 |
GT15156 |
Neuromics |
100 ug |
EUR 631.2 |
CXCL8/IL-8 |
E21-C97 |
EnoGene |
10ug |
EUR 411.6 |
Recombinant Human Interleuikin-8 (1-72) (CXCL8) |
7-01906 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Interleuikin-8 (1-72) (CXCL8) |
7-01907 |
CHI Scientific |
25µg |
Ask for price |
Recombinant Human Interleuikin-8 (1-72) (CXCL8) |
7-01908 |
CHI Scientific |
1mg |
Ask for price |
Recombinant Human Interleuikin-8 (1-77) (CXCL8) |
7-01912 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Interleuikin-8 (1-77) (CXCL8) |
7-01913 |
CHI Scientific |
25µg |
Ask for price |
Recombinant Human Interleuikin-8 (1-77) (CXCL8) |
7-01914 |
CHI Scientific |
1mg |
Ask for price |
Human Interleuikin-8 (1-72) (CXCL8) , (Recombinant) |
22060369-1 |
Bio-WORLD |
5 µg |
EUR 146.42 |
Human Interleuikin-8 (1-77) (CXCL8) , (Recombinant) |
22060370-1 |
Bio-WORLD |
5 µg |
EUR 146.42 |
Recombinant Human IL8/CXCL8 Protein, Fc Tag |
E40KMH119 |
EnoGene |
20ug |
EUR 495 |
Description: Recombinant Human Cytotoxic T-lymphocyte Protein 4 is produced by our Mammalian expression system and the target gene encoding Lys36-Asp161 is expressed with a Flag tag at the C-terminus. |
CXCL8 Antibody, HRP conjugated |
1-CSB-PA15789B0Rb |
Cusabio |
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Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Gallus gallus. This antibody is HRP conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, HRP conjugated |
1-CSB-PA08327B0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, HRP conjugated |
1-CSB-PA08329B0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, HRP conjugated |
1-CSB-PA011671YB01DO |
Cusabio |
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|
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Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from dog. This antibody is HRP conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, FITC conjugated |
1-CSB-PA15789C0Rb |
Cusabio |
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Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Gallus gallus. This antibody is FITC conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, FITC conjugated |
1-CSB-PA08327C0Rb |
Cusabio |
|
|
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Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, FITC conjugated |
1-CSB-PA08329C0Rb |
Cusabio |
|
|
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Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, FITC conjugated |
1-CSB-PA011671YC01DO |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from dog. This antibody is FITC conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, Biotin conjugated |
1-CSB-PA15789D0Rb |
Cusabio |
|
|
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Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Gallus gallus. This antibody is Biotin conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, Biotin conjugated |
1-CSB-PA08327D0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, Biotin conjugated |
1-CSB-PA08329D0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
CXCL8 Antibody, Biotin conjugated |
1-CSB-PA011671YD01DO |
Cusabio |
|
|
|
Description: A polyclonal antibody against CXCL8. Recognizes CXCL8 from dog. This antibody is Biotin conjugated. Tested in the following application: ELISA |
- In accordance with this, utilizing lysates of extremely purified (>90%) pores and skin mast cells, we might display that each TNF-alpha and IL-Eight mRNA and protein had been current in each unstimulated in addition to stimulated mast cells. In stark distinction to those outcomes, no important ranges of both IL-4, IL-5 or IL-13 had been detected, whatever the secretagogue used or the interval of stimulation.
- These outcomes present that human pores and skin mast cells are able to quickly secreting pro-inflammatory cytokines like TNF-alpha and IL-Eight following IgE-dependent activation and stimulation by the neuropeptide substance P, SCF and the essential polypeptide analogue compound 48/80. In distinction to different forms of human mast cells nonetheless, human pores and skin mast cells had been incapable of secreting IL-4, IL-5 or IL-13 in these settings.