ELISA Strip

Anti Podoplanin antibody

Posted on by Bianca

Anti-Podoplanin antibody

 

  • Antibody-drug conjugates (ADCs), which encompass a monoclonal antibody (mAb), a linker, and a payload, can ship a drug to most cancers tissues. We beforehand produced an anti-dog podoplanin (dPDPN) mAb, PMab-38, which reacts with dPDPN-expressing canine melanomas and squamous cell carcinomas (SCCs), however not with dPDPN-expressing canine sort I alveolar cells or lymphatic endothelial cells, indicating that PMab-38 possesses most cancers specificity.

 

  • On this examine, we developed an ADC, P38B-DM1, utilizing the mouse-canine chimeric anti-dPDPN antibody, P38B because the antibody, a peptide linker, and emtansine because the payload utilizing the chemical conjugation by affinity peptide (CCAP) methodology.

 

  • We investigated its cytotoxicity towards dPDPN–overexpressed Chinese language hamster ovary (CHO/dPDPN) cells in vitro and its antitumor exercise utilizing a mouse xenograft mannequin of CHO/dPDPN cells. P38B-DM1 confirmed cytotoxicity to CHO/dPDPN cells in a dose-dependent method in vitro.

Rabbit Polyclonal antibody Anti-CRBN

  • Moreover, P38B-DM1 exhibited larger antitumor exercise than P38B within the mouse xenograft mannequin. These outcomes counsel that P38B-DM1, developed utilizing the CCAP methodology, is helpful for antibody remedy towards dPDPN-expressing canine SCCs and melanomas.

 

 

 

Anti-Podoplanin/gp36/PDPN Antibody

 

  • Podoplanin (PDPN) is a kind I transmembrane intently glycosylated sialoglycoprotein that is expressed in common tissues much like pulmonary type I alveolar cells, renal podocytes, and lymphatic endothelial cells. PDPN overexpression in cancerous tissue is said to hematogenous metastasis by way of interactions with the C-type lectin-like receptor 2 (CLEC-2). Beforehand, we’ve now reported the occasion of a mouse monoclonal antibody (mAb), PMab-38 (IgG1, kappa) in the direction of canine PDPN (dPDPN).

anti- Podoplanin antibody
FNab06598 100µg
EUR 585
  • Recommended dilution: WB: 1:500-1:2000
  • IHC: 1:20-1:200
  • Immunogen: podoplanin
  • Uniprot ID: Q86YL7
  • Research Area: Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Description: Antibody raised against Podoplanin

anti- Podoplanin antibody
FNab06599 100µg
EUR 585
  • Recommended dilution: WB: 1:500 - 1:2000
  • Immunogen: PDPN
  • Uniprot ID: Q86YL7
  • Research Area: Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Description: Antibody raised against Podoplanin

Anti-Podoplanin antibody
PAab06598 100 ug
EUR 412

Anti-Podoplanin antibody
PAab06599 100 ug
EUR 412

Anti-Podoplanin antibody
STJ180226 0.1 ml
EUR 266

Anti-Podoplanin antibody
STJ180283 0.1 ml
EUR 223

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 349

Podoplanin
MO47016 100 ul
EUR 349

Anti-Podoplanin/gp36/PDPN Antibody
A01124 100ug/vial
EUR 294

Anti-Podoplanin/gp36/PDPN Antibody
PA1411 100ug/vial
EUR 294

Anti-Podoplanin/gp36/PDPN Antibody
PA1674 100ug/vial
EUR 294

Anti-Podoplanin/gp36/PDPN Antibody
PA1675 100ug/vial
EUR 294

Anti-Podoplanin Rabbit Monoclonal Antibody
M01124-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Podoplanin Rabbit Monoclonal Antibody
M01124-2 100ug/vial
EUR 397
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human.

Anti-D2-40 Podoplanin antibody
STJ16100360 1 mL
EUR 1235

Anti-D2-40/Podoplanin antibody
STJ190048 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to D2-40/Podoplanin (7D1)

Mouse Podoplanin ELISA kit
E03P0082-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit
E03P0082-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit
E03P0082-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin (PDPN) Protein
20-abx650139
  • EUR 648.00
  • EUR 272.00
  • EUR 1943.00
  • EUR 759.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Anti-Human Podoplanin monoclonal antibody, clone JID761
CABT-L2919-100uL500uL 100 uL, 500 uL
EUR 502

Podoplanin antibody
70R-11540 100 ug
EUR 527
Description: Rabbit polyclonal Podoplanin antibody

Podoplanin antibody
70R-13952 100 ug
EUR 305
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Podoplanin antibody
10R-P133a 100 ug
EUR 507
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody
10R-P155a 100 ug
EUR 543
Description: Hamster monoclonal Podoplanin antibody

Podoplanin antibody
10R-7662 100 ug
EUR 629
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody
10R-7663 100 ug
EUR 629
Description: Hamster monoclonal Podoplanin antibody

Podoplanin antibody
10R-7664 100 ug
EUR 629
Description: Mouse monoclonal Podoplanin antibody

Podoplanin Antibody
49474-100ul 100ul
EUR 333

Podoplanin Antibody
49474-50ul 50ul
EUR 239

Podoplanin Antibody
DF12456 200ul
EUR 304
Description: Podoplanin antibody detects endogenous levels of Podoplanin.

Podoplanin antibody
70R-PR007 100 ug
EUR 422
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Podoplanin antibody
70R-50819 100 ul
EUR 244
Description: Purified Polyclonal Podoplanin antibody

Podoplanin antibody
70R-6816 50 ug
EUR 467
Description: Rabbit polyclonal Podoplanin antibody raised against the N terminal of PDPN

Podoplanin antibody
70R-6817 50 ug
EUR 467
Description: Rabbit polyclonal Podoplanin antibody raised against the middle region of PDPN

Podoplanin Antibody
P1051-01m 0.1m
EUR 209

Podoplanin Antibody
P1051-1ml 1ml
EUR 941

Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form
GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 280

Mouse Podoplanin (PDPN) ELISA Kit
DLR-PDPN-Mu-48T 48T
EUR 527
  • Should the Mouse Podoplanin (PDPN) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
DLR-PDPN-Mu-96T 96T
EUR 688
  • Should the Mouse Podoplanin (PDPN) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Recombinant Mouse Podoplanin (C-Fc)
CU73-10ug 10ug
EUR 131
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)
CU73-1mg 1mg
EUR 1674
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)
CU73-500ug 500ug
EUR 1166
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)
CU73-50ug 50ug
EUR 273
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Mouse Podoplanin (PDPN) ELISA Kit
20-abx154564
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Mouse Podoplanin, Pdpn ELISA KIT
ELI-06723m 96 Tests
EUR 865

 

  • PMab-38 was found to strongly react with canine squamous cell carcinomas (SCCs) and melanomas; nonetheless, it confirmed no response with lymphatic endothelial cells. Simply recently, we’ve now developed and produced the mouse-canine mAb of subclass B, P38B that confirmed antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity in the direction of Chinese language language hamster ovary (CHO)/dPDPN cells. Throughout the present analysis, we investigated the antitumor train using mouse xenograft model.

 

  • To induce ADCC train by P38B, canine mononuclear cells have been injected surrounding the tumors in a xenograft model. It was demonstrated that P38B exerted antitumor train in the direction of the mouse xenograft model using CHO/dPDPN. These outcomes suggest that P38B is useful for antibody treatment in the direction of dPDPN-expressing canine SCCs and melanomas.

 

Anti-Podoplanin Antibody
A1564-100
EUR 479
anti- Podoplanin antibody
FNab06598 100µg
EUR 585
  • Recommended dilution: WB: 1:500-1:2000
  • IHC: 1:20-1:200
  • Immunogen: podoplanin
  • Uniprot ID: Q86YL7
  • Research Area: Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Description: Antibody raised against Podoplanin
anti- Podoplanin antibody
FNab06599 100µg
EUR 585
  • Recommended dilution: WB: 1:500 - 1:2000
  • Immunogen: PDPN
  • Uniprot ID: Q86YL7
  • Research Area: Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Description: Antibody raised against Podoplanin
Anti-Podoplanin antibody
PAab06598 100 ug
EUR 412
Anti-Podoplanin antibody
PAab06599 100 ug
EUR 412
Anti-Podoplanin antibody
STJ180226 0.1 ml
EUR 266
Anti-Podoplanin antibody
STJ180283 0.1 ml
EUR 223
Hamster Mono Anti-Mouse CD3e IgG (Hamster IgG)
MCD003E-M 100 Tests
EUR 482
Hamster Mono Anti-Mouse CD3z IgG (Hamster IgG)
MCD003Z-M 100 ug
EUR 482
Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 349
Hamster Mono Anti-Mouse CD25 , Pur. Low Endotoxin (Hamster IgG)
MCD027-M 100 ug
EUR 482
Podoplanin
MO47016 100 ul
EUR 349
Mouse Anti Hamster Marco Monoclonal Antibody
DMABT-47716MH 0.25 mg
EUR 741
mAb hamster anti-mouse IL-9
CT327 0.5 mg
EUR 260
Hamster Anti Mouse Cd152 Monoclonal Antibody
CABT-47114HM 0.1 mg
EUR 455
Hamster Anti Mouse Cd154 Monoclonal Antibody
CABT-47157HM 0.1 mg
EUR 455
Hamster Anti Mouse Cd178 Monoclonal Antibody
CABT-47221HM 0.1 mg
EUR 455
Hamster Anti Mouse Cd195 Monoclonal Antibody
CABT-47249HM 0.25 mg
EUR 663
Hamster Anti Mouse Cd28 Monoclonal Antibody
CABT-48079HM 0.2 mg
EUR 663
Hamster Anti Mouse Cd81 Monoclonal Antibody
CABT-48269HM 0.1 mg
EUR 455
Hamster Anti Mouse Cd339 Monoclonal Antibody
CABT-49800HM 0.1 mg
EUR 455
Hamster Anti Mouse Jagged2 Monoclonal Antibody
CABT-49812HM 0.1 mg
EUR 455
Hamster Anti Mouse Bim Monoclonal Antibody
CABT-50130HM 0.1 mg
EUR 559
Hamster Anti Mouse Cd278 Monoclonal Antibody
CABT-51735HM 0.25 mg
EUR 663
Hamster Anti Mouse Cd27 Monoclonal Antibody
CABT-54688HM 0.25 mg
EUR 663
Hamster Anti Mouse Cd29 Monoclonal Antibody
CABT-45874HM 0.1 mg
EUR 455
Hamster Anti CD28 Antibody
20-abx137056
  • EUR 356.00
  • EUR 523.00
  • 0.5 mg
  • 1 mg
  • Shipped within 5-10 working days.
Hamster Mono Anti-Mouse CD3e, Biotin (Clone 145-2C11) (hamster IgG)
MCD003E-B 100 tests
EUR 469
Hamster Mono Anti-Mouse CD3e, FITC (Clone 145-2C11) (hamster IgG)
MCD003E-F 100 tests
EUR 469
Hamster Mono Anti-Mouse CD3z, Biotin (Clone H146-968) (hamster IgG)
MCD003Z-B 100 tests
EUR 469
Hamster Mono Anti-Mouse CD3z, FITC (Clone H146-968) (hamster IgG)
MCD003Z-F 100 tests
EUR 469
Hamster Mono Anti-Mouse CD3z, PE (Clone H146-968) (hamster IgG)
MCD003Z-PE 100 tests
EUR 469
Anti-Podoplanin/gp36/PDPN Antibody
A01124 100ug/vial
EUR 294
Anti-Podoplanin/gp36/PDPN Antibody
PA1411 100ug/vial
EUR 294
Anti-Podoplanin/gp36/PDPN Antibody
PA1674 100ug/vial
EUR 294
Anti-Podoplanin/gp36/PDPN Antibody
PA1675 100ug/vial
EUR 294
Anti-Podoplanin Rabbit Monoclonal Antibody
M01124-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human, Mouse, Rat.
Anti-Podoplanin Rabbit Monoclonal Antibody
M01124-2 100ug/vial
EUR 397
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human.
Anti-D2-40 Podoplanin antibody
STJ16100360 1 mL
EUR 1235
Anti-D2-40/Podoplanin antibody
STJ190048 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to D2-40/Podoplanin (7D1)
Hamster Mono Anti-Mouse CD27 Biotin (Clone LG.3A10) (Armenian Hamster IgG1)
MCD027-B 100 tests
EUR 469
Hamster Mono Anti-Mouse CD27 FITC (Clone LG.3A10) (Armenian Hamster IgG1)
MCD027-F 50 Tests
EUR 408
Hamster Mono Anti-Mouse CD27 PE (Clone LG.3A10) (Armenian Hamster IgG1)
MCD027-PE 50 tests
EUR 347
Mouse Podoplanin ELISA kit
E03P0082-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Podoplanin ELISA kit
E03P0082-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Anti-Podoplanin Rabbit Monoclonal Antibody
  • Podoplanin is expressed in a lot of cancers, along with oral cancers and thoughts tumors. The interaction between podoplanin and its receptor C-type lectin-like receptor 2 (CLEC-2) has been reported to be involved in most cancers metastasis and tumor malignancy. We beforehand established many monoclonal antibodies (mAbs) in the direction of human podoplanin using the cancer-specific mAb (CasMab) experience. LpMab-23 (IgG1, kappa), one in every of many mouse anti-podoplanin mAbs, was confirmed to be a CasMab.

 

  • Nonetheless, we’ve no longer confirmed the usefulness of LpMab-23 for antibody treatment in the direction of podoplanin-expressing cancers. On this analysis, we first determined the minimal epitope of LpMab-23 and revealed that Gly54-Leu64 peptide, notably Gly54, Thr55, Ser56, Glu57, Asp58, Arg59, Tyr60, and Leu64 of podoplanin, is a important epitope of LpMab-23. We further produced human-mouse chimeric LpMab-23 (chLpMab-23) and investigated whether or not or not chLpMab-23 exerts antibody-dependent cellular cytotoxicity (ADCC) and antitumor train.

    Anti-D2-40 Podoplanin antibody
  • In stream cytometry, chLpMab-23 confirmed extreme sensitivity in the direction of a podoplanin-expressing glioblastoma cell line, LN319, and an oral most cancers cell line, HSC-2. chLpMab-23 moreover confirmed ADCC train in the direction of podoplanin-expressing CHO cells (CHO/podoplanin). In xenograft fashions with HSC-2 and CHO/podoplanin, chLpMab-23 exerts antitumor train using human pure killer cells, indicating that chLpMab-23 could very nicely be useful for antibody treatment in the direction of podoplanin-expressing cancers.

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